The Ultimate Guide to the Best Kratom for Anxiety and Depression in 2023

Kratom, a botanical substance that has captured the attention of many seeking alternative remedies, has been at the center of discussions and debates regarding its potential therapeutic uses, particularly for managing anxiety and depression symptoms. Despite its growing popularity, considerable ambiguity remains about how kratom works, what strains are best for specific ailments, and its safety profile. This necessitates a critical examination of kratom, its effects, and its suitability as a self-treatment for emotional distress.

Given the global prevalence of mental health issues, exploring unconventional options like kratom may provide valuable insights to those struggling with depression and anxiety. However, it is essential to approach this subject with caution. The FDA hasn’t approved kratom for medical use, and there are notable gaps in scientific research regarding kratom’s efficacy and safety. Consequently, this article aims to inform rather than endorse, urging readers to consider professional medical advice alongside their interest in kratom.

Understanding Kratom

Kratom, scientifically known as Mitragyna speciosa, is a tropical evergreen tree from Southeast Asia. For centuries, locals have traditionally used it for its medicinal properties. Today, it is available globally in various forms, such as kratom powder, capsules, and kratom tea.

Origin and Traditional Uses of Kratom

Tracing its roots to Thailand, Malaysia, Indonesia, Myanmar, and Papua New Guinea, kratom has a robust historical presence in traditional medicine. Rural communities would often chew the raw leaves or prepare a brewed concoction to improve their work productivity, alleviate fatigue, or as a substitute in opioid withdrawal cases.

How Kratom Works: The Active Ingredients

The therapeutic potential of kratom largely derives from the presence of two primary alkaloids: mitragynine and 7-hydroxy mitragynine. These compounds have an affinity for opioid receptors in the brain. Mitragynine primarily exerts a stimulant effect at lower doses, while the sedative effect of both compounds becomes prominent at higher doses. These effects have piqued the interest of those seeking relief from depression and anxiety symptoms.

Different Strains and Their General Effects

Diverse in nature, different strains of kratom impart varying effects that make particular varieties more suitable for specific needs. Generally categorized by leaf vein color (red, green, or white), these strains differ in alkaloid concentration:

  • Red vein kratom strains often provide a strong sedative effect.
  • White strains are known for their stimulating and mood-enhancing properties.
  • Green kratom strains strike a balance between relaxation and energy.

Knowing these distinctions can aid enthusiasts and patients in seeking the right type of kratom that aligns with their health objectives. Whether one aims to invigorate themselves or experience calming relief, the myriad of strains of kratom offers a spectrum of choices.

As we delve further into the specific kratom varieties recommended for battling anxiety and depression, it is crucial to consider existing anecdotal evidence while remaining cognizant that access to approved kratom products for therapeutic uses remains constrained by regulatory guidelines. Therefore, anyone contemplating the use of kratom for anxiety and depression should conduct thorough research and consult healthcare professionals before embarking on this path.

Kratom and Mental Health

Overview of Studies and Surveys on Kratom Use for Mental Health

While kratom has historically been used for its stimulant and analgesic properties, an emerging body of anecdotal evidence and some scientific studies suggest its potential to alleviate mental health issues, such as depression and anxiety. According to a 2017 review published in Drug and Alcohol Dependencekratom appears to have mood-enhancing effects and may help ease withdrawal from opioid dependence.

Other surveys, including research supported by Johns Hopkins Medicine, reveal that many individuals use kratom for self-treatment of mental health conditions, notably anxiety and depression, with some success. This suggests that kratom’s mood-lifting and anxiolytic properties have resonated with users, leading them to consider it a viable alternative remedy; however, such use is not without risk or controversy.

Discussion on How Kratom Users Report Relief from Anxiety and Depression Symptoms

Users often describe the effects of kratom as similar to those of prescription anxiolytics and antidepressants. Specifically, they note an anxiety reduction, improved mood, increased sociability, and an overall sense of well-being upon using specific strains of kratom. For example, the sedative effect found in certain strains may help manage anxiety symptoms, potentially making social interactions more comfortable for those with social anxiety disorder.

In addition to its mood-stabilizing effects, some kratom users also report that it can help alleviate physical signs of stress, such as muscle tension, which often accompanies anxiety and stress. This dual action—both psychological and physiological—could explain why certain individuals find it useful for their mental health concerns.

Mention of the Need for More Clinical Studies

Despite these positive anecdotal reports, it is essential to recognize the limitations of the existing evidence base. Most available data comes from user self-reports or observational studies. The scientific community has yet to conduct large-scale, controlled clinical trials to fully understand how kratom may interact with the body, notably concerning mental health. There are also significant concerns regarding kratom’s safety profile, potential for abuse, and legal status in various regions. This persistently emphasizes the need for caution and further research.

Best Kratom Strains for Anxiety and Depression

Maeng Da

Maeng Da Kratom is a potent strain renowned for its energizing, solid effects. Nevertheless, when taken in moderated doses, it can also offer an anti-anxiety impact without leading to sedation. As one of the most powerful strains available, Maeng Da’s balance between alleviating mood disorders and boosting energy makes it a popular choice for those facing the dual challenges of lethargy and emotional turmoil brought on by depression or anxiety.

Red Thai

Originating from Thailand, Red Thai is deemed particularly effective against stress-related anxiety symptoms. Its claim to fame rests in its ability to induce serenity and calmness. The strain’s pronounced sedative effect can also extend to relief from physical discomfort often linked with emotional distress.

Red Malay

Another strain that is held in high regard within the kratom community is Red Malay, who hails from Malaysia. It is acclaimed for its long-lasting tranquilizing effect that can be pivotal in managing persistent anxiety disorders. As it offers a sustained relaxing experience without the overt drowsiness of some other red strains, Red Malay fits nicely into the regimens of those needing prolonged relief with minimal impact on day-to-day activities.

Red Bali

Praised for its accessibility and affordability, Red Bali Kratom stands out with its versatility. It is commonly recommended for first-time users due to its gentle nature but noticeable efficacy in subduing apprehension and promoting relaxation. Particularly in cases of temporary bouts of stress or as a nighttime strain to combat sleep-related issues due to anxiety, Red Bali has won favor among the kratom community.

Green Vietnam

A relatively new addition compared to the historic strains from Thailand or Malaysia, Green Vietnam Kratom derives its uniqueness from its balanced profile. It is an adaptable strain that combines a soothing sedative effect with mild stimulation, making it apt for those seeking relief during work hours or social events without an overpowering sense of drowsiness.

For each recommended strain, acknowledging their geographical origins gives insight into the diversity of effects across different types of kratom and their suitability for managing symptoms of depression and anxiety. Moreover, these strains have gained reputations for their perceived benefits within the user communities.

Dosage and Side Effects

Taking kratom at the proper dosage is crucial to maximize its potential benefits while minimizing adverse effects. However, the optimal dose can vary significantly among individuals due to factors like personal tolerance, the specific kratom strain used, and the method of consumption. Whether it is kratom powder, capsules, or tea, each form requires different dosages to achieve the desired effects.

General Guidelines for Kratom Dosage

Below are general dosage suggestions based on average user experiences:

  • Low dose (1-5 grams): Often produces a stimulant effect, improving energy and focus.
  • Moderate dose (5-15 grams): Typically associated with pain relief and sedation and may help with anxiety.
  • High dose (15-25 grams): Likely to produce sedative solid effects and is not commonly recommended due to the increased risk of side effects.

It is essential to start with the lowest possible dose, especially if you are new to using kratom, and gradually increase as necessary to find the one that works best for you while monitoring your body’s response.

Potential Side Effects and Risks of Kratom Use

While some find kratom beneficial, it does have a spectrum of potential side effects. These may include:

  • Nausea
  • Dizziness
  • Constipation
  • Dependency
  • Withdrawal symptoms upon stopping kratom use
  • More severe complications when combined with other drugs or medications

Long-term or high-dose use of kratom further raises the risks of experiencing adverse side effects, which could be particularly concerning for individuals with preexisting health conditions or those taking other medications.

Importance of Using Kratom Responsibly and Under Medical Supervision

Users should always exercise caution and ideally consult a healthcare professional before integrating kratom into their regimen for managing anxiety and depression symptoms. Given its potential interactions with other substances and the risk of dependency, using kratom responsibly is paramount. Additionally, since quality can vary among suppliers, it’s essential to source kratom products from reputable providers.


In concluding this exploration into kratom for anxiety and depression, it’s clear from anecdotal reports and early-stage research that certain strains of kratom may provide relief for those struggling with mental health conditions. Strains such as Maeng DaRed ThaiRed MalayRed Bali, and Green Vietnam have been identified by users as potentially beneficial in managing symptoms of these conditions.

Nevertheless, it’s imperative to reiterate that kratom is not FDA-approved, its clinical efficacy remains under investigation, and there are significant safety concerns associated with its use. While users have reported positive experiences with controlled, low-to-moderate doses, kratom’s varying legal status, diverse effects depending on strains and dosage, potential risk of dependency, and other side effects cannot be overlooked.

For anyone considering kratom for their mental health struggles, we strongly emphasize the importance of doing so with caution and under the guidance of a medical professional. Moreover, this highlights the critical need for more robust research to deepen our understanding of how kratom can be used safely and effectively.

Though the journey toward establishing kratom’s place in mental health treatment is still unfolding, our continuum of learning underscores the value of informed choice in pursuing personal wellness.

To continue your research or purchase quality strains, visit Native Natures, and always start low and go slow as you navigate your path with kratom. For further guidance on dosing safely and effectively, check out our detailed Kratom Dosage Guide.

Native Natures

The mission is to empower our readers with the knowledge and tools they need to take control of their health naturally. We believe that a well-informed individual is better equipped to make choices that promote overall well-being. At, we believe that the gifts of Mother Nature hold incredible potential in improving our well-being. With an ever-growing interest in natural remedies, we decided to create this platform to share our knowledge, experiences, and research about the various plant-based alternatives available to us. As passionate proponents of natural remedies, we understand the importance of finding reliable information in a world full of misinformation. was born out of the desire to provide a trustworthy source where readers can access accurate, up-to-date, and unbiased content related to CBD, Delta 9, Kratom, tinctures, and other natural solutions.

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